Absorption and Drug Development: Solubility, Permeability, and Charge State by Alex Avdeef

Absorption and Drug Development: Solubility, Permeability, and Charge State



Download Absorption and Drug Development: Solubility, Permeability, and Charge State




Absorption and Drug Development: Solubility, Permeability, and Charge State Alex Avdeef
Language: English
Page: 312
Format: pdf
ISBN: 0471423653, 9780471423652
Publisher: Wiley-Interscience

Many times drugs work fine when tested outside the body, but when they are tested in the body they fail. One of the major reasons a drug fails is that it cannot be absorb by the body in a way to have the effect it was intended to have. Permeability, Solubility, Dissolution, and Charged State of Ionizable Molecules:Helps drug discovery professionals to eliminate poorly absorbable molecules early in the drug discovery process, which can save drug companies millions of dollars.Extensive tabulations, in appendix format, of properties and structures of about 200 standard drug molecules.

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